In the movie, when Garry Shandling and Téa Leoni are kissing in the grave she says, "no bees," regarding the bee that interrupts what might have been the first love kiss between Mulder and Scully.
Scully tells Mulder that she thinks Téa Leoni has a crush on him, and Mulder wonders how she could. Téa Leoni was David Duchovny's wife in real life at the time.
Scully asks Mulder how many times he's seen Plan 9 from Outer Space (1957), to which he replies "42". This is a long-running geek reference from The Hitchhiker's Guide to the Galaxy as "The Answer to the Ultimate Question of Life, The Universe, and Everything." It's also Mulder's apartment number.
Chris Carter, Minnie Driver and David Alan Grier are in the audience watching the premiere. Driver and Grier star alongside David Duchovny in Return to Me (2000) which was released a couple of weeks before this episode aired.