It is mentioned that Ktarians, like Klingons, are prone to growing faster than humans. This is the show's way of explaining how Naomi Wildman has grown so much despite being born only a year and a half earlier. The reason Klingons are mentioned is because this was also the case in Star Trek: The Next Generation (1987), when Worf's son Alexander appeared (played by a 5-6 year old actor) less than two years after being conceived. Alexander later appeared again in Star Trek: Deep Space Nine (1993) as a young adult warrior, despite the character being roughly 10-11 chronological years old.
Naomi Wildman's first name is finally revealed, a year and a half after her birth, which is depicted in Deadlock (1996).
This episode takes its name from part of the "To be, or not to be" soliloquy from William Shakespeare's play Hamlet: "For in that sleep of death what dreams may come / When we have shuffled off this mortal coil, / Must give us pause..."
Neelix's "vision quest" dream -particularly the latter portion, where spirit guides, represented by the Voyager crew, walk past Neelix and incrementally tell him what they want him to know -bears a strong resemblance to the visions that Ben Sisko has as Emissary to the Prophets on Voyager's sister series, Star Trek: Deep Space Nine (1993).
This takes place in 2374.