The script was being prepped for shooting under the title "Wink of an Eye" when production realized that there was already a show called Wink of an Eye (1968). Furthering the coincidence, both stories feature aliens existing at a much faster rate who visit the ship and see the slower crew apparently "frozen."
The large domed building on the left side of the final shot is an image of the Bloedel Conservatory, located in Queen Elizabeth Park, Vancouver, Canada.
Daniel Dae Kim (Gotana-Retz) later played the recurring role of Corporal Chang in Star Trek: Enterprise (2001).
This is listed as one of the "Ten Essential Episodes" of Voyager in the 2008 reference book "Star Trek 101" by Paula M. Block and Terry J. Erdmann.
Chakotay tells B'Elanna that they have the unique opportunity to watch the complete development and evolution of a civilization in a relatively short period of time. In the Star Trek universe human civilization is roughly 10,400 years old, at the rate time passes on the planet, and assuming the pace of their technological development roughly mirrors Earth's, Voyager was able to watch a humanoid civilization that was in their equivalent of the Stone Age advance to becoming a warp capable civilization in just 44 days.