The scar-faced thug who bothers Dixon Hill is the first Star Trek appearance of actor Robert O'Reilly. He would make numerous appearances (most notably as the Klingon politician Gowron) throughout Star Trek: The Next Generation and Star Trek: Deep Space Nine (1993).
When Lwaxana Troi talks with the ship's computer to learn that Picard is in the Holodeck, Majel Barrett is providing both voices.
When Picard first encounters Madeline in the Holodeck, she says, "You're too much, Dix. You make it sound like you ain't seen me in a year!" It has been roughly a year since Picard last ran the Dixon Hill program.
Mick Fleetwood was such a fan of the show that he agreed to shave his trademark beard for his cameo.
This is the first episode in which the dress uniform has rank pips.