Actor Christopher Reeve played Dr Virgil Swann on Smallville. The character dies in this episode, which aired several months after after Reeve's death, so presumably he passed-away during production of this season, so they killed-off the character as well. During the television news broadcast in this episode, the reporter says many things reflective of Reeve in-real-life, such as his philanthropy and his charitable organisation, clearly as a tribute by the writers to the late actor.
The reporter who reports the story about Virgil Swann's death is named Tom Flores. Tom Flores is also the name of an associate producer for Smallville.
This is Byron Mann's second time on the show. The first time was in insurgence where he was hire to bug Luthor Corp
This is the first episode in which Lionel interacts with Lana while in his own body. However, he had a conversation with her while in Clark's body in "Transference".
This episode reveals the fate of Dr. Virgil Swann, whom Clark met in the second season episode "Rosetta". Clark's key has been missing since Dr. Swann obtained it last year in "Legacy".