This episode takes place in 2005 and 2013.
Futurama (1999) character Bender appears in this episode, saying "All right! You guys are my new best friends!" The episode takes place eight years in the future. In Season 26, released ten years after this one, there is a crossover with Futurama where Homer makes friends with Bender.
In the Simpson's 2013 future, Yale has it's own "feminist" science, in the next season this actually happens in Springfield elementary in Girls Just Want to Have Sums
The title is reference to "Futurama" another show created by Matt Groening.