Earlier in the first season, Douglas Henderson also appeared in the similarly-themed The Architects of Fear (1963) (another episode in which he was instrumental in transforming an Earth man into an alien from another world).
The title refers to a type of horned lizard who has parrot-like feet and stereoscopic eyes. The species is originally found in Africa and on the Iberian peninsula, but has been transplanted to Hawaii, Florida and the southern United States. Not all varieties have the ability to adapt their coloring to that of the surrounding environment.