The odd title is an acronym for "The End of the World as We Know It".
Klea Scott recalled that, although Chris Carter professed that he had a great love for Millennium (1996) and that he was devoting as much time to it as possible, she saw him only twice during the entire run of the third season. (Carter was overseeing The X-Files (1993) and its move from Vancouver to Los Angeles at the time as well as preparing for the upcoming show Harsh Realm.)
This episode tackles the thorny issue of school shootings. Six months after it aired, the Columbine massacre took place.
Robert Wisden also appears in Millennium's episode S2E04 "Monster", but reprising a different role (Gordon Roberts).
This is the first Millennium (1996) script for both Chris Carter and Frank Spotnitz since the first season.