The title is based on the 1974 book 'Zen and the Art of Motorcycle Maintenance: An Inquiry into Values' by 'Robert M. Pirsig' about a voyage of self exploration on a motorcycle trip.
When they show a hospital entrance--the one shown is actually in Baltimore-Union Memorial, the entrance being on 33rd Street, 1 block from Johns Hopkins University. The intersection that accompanies the view of the hospital is N. Calvert and E. 33rd Streets.