- A federal agent is murdered on a plane bound for Hawaii. The investigation of this crime leads McGarrett and Five-O to uncover a terrorist plot by Dr. Erich Stoss to distribute a fungus that will wipe out the Hawaiian sugar cane crop, thereby destroying an industry and thereby forcing the U.S. and other countries to buy sugar from non-U.S. sources.—aldanoli
- On a plane bound for Hawaii, Prof Stoss kills a federal agent that is tracking him just as the plane starts to land. When McGarrett and the Five-O team arrive at the scene, the medical examiner explains the death and coupled with another federal agent`s explanation of the assignment, they conclude an act of terrorism is about to happen.
The only clue left by the dead agent is a sketch of a woman, Mariana, that the Five-O team traces to a hotel. They follow her to a chemicals shop but she elludes them out the back, only to become a victim of an automobile accident. The detectives get the chemical list from the shop proprietor and piece together what she is planning on making, a medium to cultivate a fungus.
Meanwhile, Stoss sends a henchman Lao to the hospital to get the chemical formula from Mariana, and to offer her a poison to take her life so she does not reveal the terrorist plot. She takes the poison before McGarrett arrives but manages to help him by connecting Stoss.
With a team assembled by the governor, they all conclude the Hawaiian sugar fields are the target of the fungus. The state produces about 40% of the world`s sugar supply, a tidy profit for other countries to take a firm hold of with the Hawaiian crops damaged for 5 years. In particular is Esteban`s South American country with a large surplus of sugar but no where to sell it.
The Five-O team races to find anyone with ties to the plot and access to a means to deliver the fungus such as aircraft or helicoptors. A small test batch of the fungus infects a crop and the agricultural agent orders the field burned down to prevent spreading. McGarrett traces the clues to an old island resident who owns crop dusting equipment and confronts Stoss only to be taken captive.
Stoss knows his plan is unravelling and decides to escape, but leaves a henchman with orders to kill McGarrett. The henchman is distracted by the Hawaiian farmer and McGarrett overpowers him, taking his rifle and follows Stoss, Lao and Esteban. Lao is sacrificed by Stoss as there is not room for him on the helicoptor for three to escape from the villa. McGarrett arrive and shoots Esteban, cornering Stoss, who tries to use the trick cane he has (the same weapon he killed the government agent on the plane with) to kill McGarrett. The trick almost works but McGarrett holds on and the rest of Five-O arrive to "book" Stoss. The sugar crops are safe.
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