Jane Leeves's good friend, Valerie Bertinelli, was in the studio audience and her laughter can be heard throughout the episode.
Peri Gilpin and John Mahoney also appeared during the final season of Cheers (1982). Gilpin played a reporter and Mahoney played a jingle writer.
By the 9th season, Moose, who plays Eddie, will be replaced by his son Enzo. Most of his markings are similar enough not to be noticed, but Moose's hair is shaggier than his son's.
KACL, the radio station where Frasier (Kelsey Grammer) works, owes its name to the initials of the three producers and writers of the show: David Angell, Peter Casey and David Lee. The letters are also form a homophone for "cackle", a synonym for laugh.