The movie Dr. Phlox is watching when his hallucinations first begin is The Court Jester (1955) starring Danny Kaye.
This is one of a mere few episodes of Star Trek: Enterprise (2001) (or any Star Trek series) to credit no guest stars. Due to its omission of any such performers and because only existing sets of Enterprise were used for this episode, it qualifies as a true bottle show.
This episode has a striking resemblance to One (1998), where Seven of Nine must navigate the ship through a hazardous region of space and the crew is in a comatose state. She begins to hallucinate, too.
Phlox says "I'm a Physician, not an engineer" a slightly different version of Dr.McCoy's famous line "I'm a doctor, not an engineer" from the original Star Trek (1966).
This episode was directed by Roxann Dawson, who played B'Elanna Torres in Star Trek: Voyager (1995).