The comic book Harry is reading in this episode is the same "Tales from Space" comic that Sherman Peabody shows to his father, Pa Peabody, in "Back to the Future (1985)."
Guest star Miguel Ferrer is the son of José Ferrer, who played the title role in (and won an Oscar for) the film "Cyrano de Bergerac (1950)," directed by Joseph Gordon-Levitt's grandfather, Michael Gordon.
Pitman has short hair. Two episodes later he has long hair again.
Episode title is a variant on the aphorism, "Youth is wasted on the young." (Tjn - 01/31/23)