Meredith thinks about her loyalties while Alex deals with the fallout of his actions; Amelia and Owen host a dinner party with surprising guests; Jackson makes a suggestion to help April through her recovery.
A family argues at the hospital following a car crash at a funeral; Arizona is caught between Alex and Andrew; Ben has a new parenting role; Amelia helps Meredith and Maggie work through a problem.
A familiar face returns to Grey Sloan throwing many of the doctors for a loop. With Catherine putting on the pressure, Bailey has to make a decision about Alex while a tough ER case makes Amelia's bad day even worse.
The arrival of a new consultant puts the doctors on edge; Amelia and Owen bring their personal problems into the hospital; April explores some unfamiliar territory.
Alex makes a decision about his future when it looks like he'll be going to jail. In the meantime, Richard wants to know why Eliza is at Seattle Grace as victims of a building collapse are brought in.
Maggie's mother unexpectedly visits; Bailey is forced to make a tough decision when an attending won't work with Eliza; Stephanie gets involved in Owen and Amelia's drama.
Richard, Jackson, April and Catherine tackle a grueling trauma case intensified by hospital politics; Amelia finally faces her feelings about Owen; Meredith gets caught between Nathan and Alex over a patient.
When Maggie's mom's health deteriorates, the doctors are at odds over how to treat her. Meanwhile, Richard comes to grips with Bailey's betrayal over the Residency Program.
When Maggie takes on a big case, many of the doctors are worried she's not the right one for the job; Stephanie makes the mistake of treating one of Grey Sloan's own.
Bailey and April work to fix things between Richard and Catherine; Eliza continues to pursue Arizona; one of Alex's previous patients returns to Grey-Sloan.
April and Andrew consult with a patient who has an inoperable heart tumor; Alex and Eliza disagree about the treatment of a young patient; Stephanie and Ben make major decisions.
The doctors of Grey Sloan encounter a difficult case involving a dangerous patient; Owen receives life-changing news that pushes Amelia to step up to support him; Alex attends a medical conference after making a shocking discovery.
A dangerous patient escapes the hospital room, putting the doctor's lives at risk; Alex faces a difficult decision in his relationship with Jo; Meredith has big news for Nathan.