Binky and Bongo, characters from 'Life in Hell" (a comic strip created by Matt Groening that he started before creating the Simpsons), make cameos in this game.
There's a gag in the game where Marge has bunny ears hiding under her blue hair. This was actually originally going to be revealed when the show was going to end, but was decided later on to be dropped.
Despite being a very popular and successful arcade machine, it was never ported to any home consoles. It was, however, ported to the Commodore 64 home computer.
This game was very similar and almost a clone to the Teenage Mutant Ninja Turtles arcade game.
Variant versions of the hand where ported to Commodore 64 and MS DOS.