According to Daniel Mainwaring, writer of Out of the Past (1947), RKO head Howard Hughes used this film to get rid of numerous writers, directors and actors. If they refused to work on this project, they were fired from the studio.
The Woman on Pier 13 (1949) marked the film debut of character actor William Talman, who makes a memorable impression as Bailey, a sleazy carnival worker and hit man for the Party. He would later play the sociopath killer in Ida Lupino's thriller, The Hitch-Hiker (1953) but is best known for his TV appearances on Perry Mason (1957) as the title character's courtroom rival, Hamilton Burger.
The Woman on Pier 13 (1949) was a commercial failure at the box-office, and recorded a loss of $650,000 ($8.37M in 2023). Audiences at the time didn't want to think about the communist menace. That's the main reason it was a commercial failure, just as similar efforts such as My Son John (1952)---with Robert Walker as a secret commie agent---and Big Jim McLain (1952) starring John Wayne, were largely overlooked by the public.
The Woman on Pier 13 (1949) was previewed in Los Angeles and San Francisco in 1949 under the title I Married a Communist but, owing to poor polling among preview audiences, this was dropped prior to its 1950 release. Studio head Howard Hughes finally yielded to RKO executives and after considering titles like San Francisco Melodrama, Waterfront at Midnight, Beautiful But Dangerous and Where Danger Lives (which was later used for RKO's film noir Where Danger Lives (1950) starring Faith Domergue, a Hughes discovery), he settled on The Woman on Pier 13.