- As of October 2005, has the most wins by any pitcher in the postseason (15)
- One of only two pitchers in major-league history to record both a 20-win and a 50-save season in his career.
- The Atlanta Braves acquired him as a minor-leaguer in a trade with the Detroit Tigers in 1987 for pitcher Doyle Alexander. He made the Braves' starting rotation in 1988 and pitched in the All-Star Game that season.
- Won the National League Cy Young award in 1996, winning 24 games and losing only 6.
- Children: son: John Andrew Jr. (b. 1991) and three daughters: Rachel Elizabeth (b. 1993) Carly Maria (b. 1997) and Kelly Christina (b. 1999)
- Pitcher with the Atlanta Braves (1988-2008).
- Made major league debut on 23 July 1988.
- Inducted into the Atlanta Braves Hall of Fame on June 8, 2012.
- Played the accordion at ages 4-7, since his parents were accordion teachers.
- Reached a preliminary agreement on a one-year, $5.5-million contract with the Boston Red Sox. (January 2009)
- Inducted into the National Baseball Hall of Fame in 2015.
- Inducted into the Michigan Baseball Hall of Fame in 2015 (inaugural class).
- Fox MLB analyst.
- Released by the Boston Red Sox and signed with the St. Louis Cardinals on August 19, 2009.
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