- Opened her own dance studio, Cheryl Burke Dance, in the spring of 2008.
- She began her dancing career when she began training in ballet at the age of 4 and at the age of 11 began ballroom dancing.
- Her father was American and her mother is Filipino. A 23andMe DNA test taken by Cheryl stated that her ancestry is approximately half Ashkenazi Jewish (father's side) and half "Chinese & Southeast Asian" (mother's).
- Winner, with her partner Emmitt Smith, of Dancing with the Stars (2005) [November 2006].
- Has her own clothing line.
- Received the key to the city of San Francisco, her hometown, by the mayor [2012].
- Winner, with her partner Drew Lachey, of Dancing with the Stars (2005) [February 2006].
- She and Matthew Lawrence became engaged on May 3, 2018, her birthday.
- Hostess of an infomercial for her "Disco Abs" workout system. (2009)
- Eurasian like fellow actresses Kelly Hu, Shannyn Sossamon, Vanessa Hudgens, Jessica Anderson, Devon Aoki, Moon Bloodgood, China Chow, Kristin Kreuk, Jaymee Ong, Maggie Q, Nicole Scherzinger, Monica Young and actors Anthony Begonia, Andrew Johnston, Brandon Lee, Keanu Reeves, Rob Schneider, Russell Wong and Michael Wong.
- Friends with Leah Remini.
- Daughter of Stephen Louis Burke (April 13, 1950-March 9, 2018) and Sherri Burke (née Bautista).
- Ranked #98 on the Maxim magazine Hot 100 of 2008 list.
- Taken to the hospital in Seattle on December 18, 2007 with a suspected case of appendicitis. Planning to fly home to San Francisco the next day for a second opinion with her family doctors.
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