Had a daughter, Anna-Maria Mamontova (February 4, 2011-late October 2011), with Sergey Mamontov. Anna-Maria died from meningococcus at 8 months old. Mamontov left Zakharova just 11 days after their daughter's death.
In early December 2017 she gave birth to her second daughter - six years after her first daughter, Anna-Maria, died from meningococcus at 8 months old.