- President of Twentieth Century-Fox studios, 1942-1962; chairman of the board of directors through 1969.
- His biography, "Skouras: King of Fox Studios" by Carlo Curti was published by Holloway House in paperback in 1967. It concentrated primarily on his professional dealings with Marilyn Monroe and Elizabeth Taylor.
- Father of Plato A. Skouras.
- Former hotelier, in the U.S. from 1910. President (and major stockholder) of 20th Century-Fox from 1943-62. Instigated CinemaScope.
- Is portrayed by Floyd Levine in Norma Jean & Marilyn (1996)
- Brother of George P. Skouras.
- Brother of Charles Skouras III.
- On July 17, 1950, daughter Dionysia died at a Los Angeles hospital about an hour after she fell from the fourth floor roof garden penthouse of the Fox West Coast Theatre Exchange Building, owned by her uncle, Charles Skouras.
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