- Auditioned six times for the role of Annette in Saturday Night Fever (1977) - three times for original director John G. Avildsen then, after he was fired, three more times for replacement director John Badham - before she got the role.
- Attended and graduated from the American Academy of Dramatic Arts (AADA), where she lost her native Brooklyn accent (1975). She had to relearn the accent for her role in Saturday Night Fever (1977).
- Did not gain weight for her role in Saturday Night Fever (1977), however she lost 15 lbs before the iconic film's release.
- She took drama classes with Rocky (1976) co-star Carl Weathers.
- During the second season of the fantasy sitcom Out of This World (1987), Pescow became pregnant. Since this could not be explained how her character became pregnant while her husband was away fighting a war, Pescow was filmed using only close-up shots or position so that something was hiding her pregnancy.
- Did not have a driver's license until she was 25 years old.
- In 1982-1983, she played the role of Dr. Lynn Carson on the soap opera All My Children (1970), who was the first lesbian character on a daytime serial.
- Attended and graduated from Sheepshead Bay High School in Brooklyn, New York (1972).
- Born on the same date as Robert Carradine.
- Has one son: Jack Casey Zelonka (born 1989).
- She has Russian Jewish ancestry.
- Currently resides in Los Angeles, California.
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