- Speaks three languages: Italian, English and French.
- His father is Italian and his mother is Algerian.
- He was born in Palermo but spent his childhood in Ethiopia. He and his family went back to Italy in 1977, when Haile Mariam Mengistu took power.
- Has directed Tilda Swinton in five productions: The Protagonists (1999), Tilda Swinton: The Love Factory (2002), I Am Love (2009), A Bigger Splash (2015) and Suspiria (2018). Swinton also helped him to create the concept of the short film Here (2012).
- Directed one Oscar nominated performance: Timothée Chalamet.
- He has never learned how to swim.
- Member of the 'Official Competition' jury at the 67th Venice International Film Festival in 2010.
- Has worked with editor Walter Fasano in 12 productions: Qui (1997), The Protagonists (1999), L'uomo risacca (2000), Mundo Civilizado (2003), Melissa P. (2005), I Am Love (2009), Chronology (2010), Destinée (2012), Bertolucci on Bertolucci (2013), A Bigger Splash (2015), Call Me by Your Name (2017) and Suspiria (2018).
- Started shooting Suspiria (2018) only four months after wrapping filming Call Me by Your Name (2017) in 2016.
- He has worked with the two leading actors of the Dune franchise: Timothée Chalamet in Call Me by Your Name (2017) and Kyle MacLachlan in The Staggering Girl (2019).
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