- Married fellow actor Billie Piper at the Parish Church of St. Mary's in Easebourne, West Sussex on New Year's Eve. They met while starring in the West End play, "Treats". (2007)
- David Tennant attended Fox's wedding to former Doctor Who (2005) co-star Billie Piper (December 2007).
- In 2021, he ran for Mayor of London, saying "I look forward to speaking up for those who are being dominated into silence." He got 1.8% of the vote, and lost his deposit.
- In 2020, after being involved in a string of controversies related to his political views, he was dropped by his agents Authentic Talent and ARG.
- Announced his separation from his wife of almost 9 years Billie Piper. No other parties were involved (23 March 2016).
- His second child (with Billie Piper), a boy named Eugene Pip Fox, was born on April 5, 2012.
- He played King George VI in W.E. (2011), in which his father James Fox played King George V. His uncle Edward Fox had previously played George VI's elder brother and predecessor King Edward VIII (the Duke of Windsor) in Edward & Mrs. Simpson (1978).
- First child, a boy named Winston James Fox, was born on October 21, 2008. He weighed 6 lbs. 11 oz. Mother is Billie Piper.
- Attended the Royal Academy of Dramatic Art.
- He is great friends with Matthew Goode.
- He played King Charles III in Whatever Love Means (2005) and his maternal grandfather King George VI in W.E. (2011). His father James Fox played the latter's father King George V in the same film. Furthermore, his cousin Emilia Fox played Queen Elizabeth II, Prince Charles' mother and King George VI's daughter, in The Queen (2009) whereas his uncle Edward Fox played the latter's elder brother and predecessor King Edward VIII (the Duke of Windsor) in Edward & Mrs. Simpson (1978).
- Was scheduled to speak at the "Counter Conference" in London in December 2021, along with Nigel Farage and U.S. politicians who support Donald Trump. It was canceled when fewer than 400 tickets were sold (the venue seats 3,000). Fox said, "We will not give up on our initiatives to take back our Western birthrights and the Counter Conference will be held in the coming months bigger than ever.".
- On 4 October 2023 he was sacked by GB News from a political opinion programme which he presented, because of offensive remarks that he made on-air about a female journalist, Ava Evans.
- Both he and his uncle Edward Fox appeared in films which depicted Operation Market Garden in September 1944: Edward played General Brian Horrocks in A Bridge Too Far (1977) while Laurence played Sturmbannführer Klaus Kessler in The Last Drop (2006).
- Son-in-law of Paul Piper.
- In September 2020, he confirmed reports that he was to start his own political party, and that it was to be provisionally titled Reclaim.
- Went to drama school with and was in the same year as fellow RADA actress Katherine Heath.
- Attempted to run for London Mayor in 2024 but only submitted 9 nominations instead of the required 10 (and 3 of his subscribers could not be reconciled to voter register records). Fox responded by saying, "I can understand why they would try and stop me standing on the platform of putting them all out of their useless jobs... This is pure political corruption".
- Born on exactly the same date as Benji Gregory (of "ALF" fame).
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