Jennifer Aniston and Jimmy Fallon in Saturday Night Live: The Best of Jimmy Fallon (2005)

Jimmy Fallon and Paris Hilton in Saturday Night Live: The Best of Jimmy Fallon (2005)

Justin Timberlake and Jimmy Fallon in Saturday Night Live: The Best of Jimmy Fallon (2005)

Seann William Scott and Jimmy Fallon in Saturday Night Live: The Best of Jimmy Fallon (2005)

Jimmy Fallon in Saturday Night Live: The Best of Jimmy Fallon (2005)

Jimmy Fallon and Halsey in Halsey/Leslie Jones/Claire Saffitz (2020)

Jimmy Fallon in The Tonight Show Starring Jimmy Fallon (2014)

Jimmy Fallon and Margot Robbie in The Tonight Show Starring Jimmy Fallon (2014)

Jimmy Fallon and Maggie Rogers in Phil McGraw/Sophia Bush/Tyler 'Ninja' Blevins/Maggie Rogers (2019)

Norm MacDonald and Jimmy Fallon in The Tonight Show Starring Jimmy Fallon (2014)

Jimmy Fallon and Tina Fey in Saturday Night Live (1975)

Jimmy Fallon in Saturday Night Live (1975)

Fred Armisen, Rachel Dratch, Jimmy Fallon, Lindsay Lohan, Amy Poehler, and Horatio Sanz in Saturday Night Live (1975)

Keri Russell, Jimmy Fallon, and Aaron Paul in The Tonight Show Starring Jimmy Fallon (2014)

Justin Timberlake and Jimmy Fallon in Saturday Night Live (1975)

Andy Cohen and Jimmy Fallon in Jimmy Fallon (2024)

Jimmy Fallon and Sam Claflin in Jimmy Fallon & Sam Claflin (2023)

Jimmy Fallon and Sadie Sink in Rachel Dratch/Sadie Sink/Turnstile

Jimmy Fallon and Sadie Sink in Lea Michele/Sadie Sink/Dayglow (2023)

Dolly Parton and Jimmy Fallon in Dolly Parton's Mountain Magic Christmas (2022)

Jimmy Fallon and Chris Parnell in Saturday Night Live: The Best of Jimmy Fallon (2005)

Queen Latifah and Jimmy Fallon in Taxi (2004)

Drew Barrymore and Jimmy Fallon in Fever Pitch (2005)

Cary Elwes, Charlie Sheen, Valeria Golino, Lloyd Bridges, Queen Latifah, and Jimmy Fallon in Johnny Dangerously (1984)

Drew Barrymore, Queen Latifah, and Jimmy Fallon in Taxi (2004)