- When The Incredible Hulk (1977) was on the air, Bixby was very careful never to be photographed with his costar, Lou Ferrigno in his Hulk makeup because he felt for photos to get out of the two of them together would destroy the illusion to children and fans of the show that they were not the same person. The tabloids of that era were always trying to get a picture of David Banner and the Hulk creature together but were unable to do so.
- After he filed for a divorce from his first wife (Brenda Benet), his 6-year-old son died of a rare infection and, a year later, his ex-wife took her own life.
- Was first choice for the lead role of Dr. David Banner of The Incredible Hulk (1977). At first, he was uneasy about the role, but after reading some comic books, he auditioned and won the role.
- Was in a relationship with Yvonne Craig.
- Cremated and ashes scattered over the Pacific Ocean in Hawaii, USA.
- Attended Grace Cathedral in the seventh grade. In one notable incident while singing in the choir, he shot the bishop using a slingshot during one service and was kicked out of the choir.
- After graduating from Lowell High School, he attended San Francisco College to pursue a major in acting. He was asked to go to the University of California-Berkeley to major in pre-law, but dropped out.
- 1972: Won the Parents Without Partners: Exemplary Service Award for his role on The Courtship of Eddie's Father (1969).
- No star! The fact that Bill Bixby has no star on the walk of fame is shameful! All his years in Hollywood, with 3 wildly popular series and he is repeating refused a start is heartbreaking to all the fans who remember his contribution to the entertainment industry.
- His funeral in 1993 was attended by actor and comedian Bob Newhart.
- Was the only child of Wilfred Bailey Everett Bixby Jr. (1908-1971) and Jane McFarland Bixby (1911-2008).
- Was of English descent.
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