- Younger brother of Bruno Barreto.
- Because of his experience in his first film, he lobbied successfully for legislation that requires film and video makers to pay actor's dues to Indigenous people from the Amazon.
- Son of Luiz Carlos Barreto and Lucy Barreto.
- Father of Mariana (with Dora Pellegrino), Lucas (with Amanda Martins), João, born in 2006 (with Débora Kalume) and Júlia, born ca. 1979, (with Marcia Barreto).
- Ex-brother-in-law of Amy Irving.
- Uncle of Gabriel Barreto.
- He visited Argentina to be part of the member of jury in San Luis Cine International Festival. (November 2007)
- Fábio Barreto suffered a dramatic car accident on 19 December 2009. He stayed in coma since the accident and eventually died on 20 November 2019.
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