- Was initially turned down for the role of Captain Janeway on Star Trek: Voyager (1995), in favor of Geneviève Bujold. When Bujold backed out of the project two days into shooting, Mulgrew again auditioned for the role, and won it.
- Is an avid fighter against Alzheimer's disease.
- Gave up her first child (b. 1977) for adoption. They both met for the first time in 1999. Mulgrew's biological daughter is named Danielle Gaudette and works as a yoga instructor. Mulgrew and Gaudette have remained in contact ever since their first meeting.
- Fellow Star Trek: Voyager (1995) actors Ethan Phillips and Robert Picardo are among her closest friends. She remarked at a convention that they got her through Voyager's seven-year run.
- Husband Timothy Hagan proposed to her on the set of Star Trek: Voyager (1995).
- Good friends with fellow Star Trek alumnus John de Lancie ("Q").
- Received a Lucille Lortel nomination for Outstanding Lead Actress for "Tea at Five" in 2003.
- After the break-up of the original AT&T (Ma Bell) in the 1980s, Kate was the face and voice of AT&T - appearing in their national TV commercials and her voice was on their pre-recorded phone prompts.
- For the Star Trek 30th Anniversary Special, she performed a parody sketch of Star Trek: Voyager (1995) with Frasier (1993) stars David Hyde Pierce, John Mahoney, Jane Leeves and Peri Gilpin.
- At age 16, she auditioned for the London Academy of Music & Dramatic Art, England. She successfully made it to the finals, but was crushed when she was told that she was too young for the classes.
- Was friends with the late John Kennedy Jr. and attended his funeral with husband Timothy Hagan.
- The godfather of her two sons is Kevin Tighe. She and Tighe got the chance to work together in the episode 11:59 (1999).
- Children: Two sons - Ian Thomas (born 1983) and Alexander James (born 1984); two stepdaughters - Eleanor Hagan (born 1987) and Marie Hagan.
- Was married to Cleveland, Ohio politician Timothy Hagan. They were introduced to each other by her mother.
- When cast for the role of Captain Janeway, Mulgrew asked that the character's first name be changed from Nicole to Kathryn. The producers agreed.
- In 1996, she was contracted by IBM to help promote the latest release of OS/2 Warp, version 4 (previously codenamed Merlin), due to associations with Star Trek.
- Received an Outer Critics Circle nomination for Outstanding Solo Performance in "Tea at Five" in 2003.
- Won the award for Best Actress at the 29th annual Carbonell Awards for her portrayal of Katharine Hepburn in "Tea at Five".
- Has appeared with Jonathan Frakes in four different productions: Camp Nowhere (1994), Gargoyles (1994), Star Trek: Voyager (1995) and Star Trek: Nemesis (2002).
- Received Broadway.com's Audience Award for Favorite Solo Performance in "Tea at Five" in 2003.
- Won the Tracey Humanitarian Award for her performance as driven alcoholic news anchor Hillary Wheaton in On the Rocks (1992).
- Pictured as the character Captain Janeway on one of a set of 18 British commemorative postage stamps issued 13 November 2020, celebrating the "Star Trek" television and film franchise. Stamps were issued as 12 individual stamps, honoring captains and crew members; and 6 stamps in a single souvenir sheet, highlighting heroes and villains. All stamps were nondenominated and marked first class (76p on day of issue). Others honored by this set are William Shatner, Patrick Stewart, Avery Brooks, Scott Bakula, Jason Isaacs, Leonard Nimoy, Marina Sirtis, Alexander Siddig, Dominic Keating, Sonequa Martin-Green, Shazad Latif, Simon Pegg, Tom Hardy, Malcolm McDowell, David Warner, Alice Eve, and Idris Elba.
- Alumna of Stella Adler Studio of Acting.
- Kathryn Janeway's character was based on a feminist writer Elizabeth Janeway.
- Received an Honorary Doctorate of Letters for Artistic Contribution from Seton Hill University in Greensburg, Pennsylvania.
- The John R. Maxim novel "Abel Baker Charlie" has a character with her name.
- Her character on Star Trek: Voyager (1995), Captain Kathryn Janeway, is regarded by fans as having bipolar disorder because of her erratic actions. Ms. Mulgrew said she blames the writers.
- Owns/owned a chocolate colored labrador called Gracie.
- Nominated for Distinguished Performance Award for her role in "Our Leading Lady" for the 73rd Annual Drama League Awards in May 2007.
- Husband Timothy Hagan ran as the Democratic Candidate for Governor of Ohio in 2002, but lost the November 5, 2002 election.
- Has a home in Brentwood, California.
- On Batman: The Animated Series (1992), she voiced a character named Red Claw. On Star Trek: Voyager (1995), a red claw was the symbol of her character's primary enemy.
- Siblings: Tom Mulgrew, Joe Mulgrew, Jenny Mulgrew, Laura Mulgrew and Sam Mulgrew.
- Parents are Joan Virginia and Thomas James Mulgrew.
- In addition to replacing Geneviève Bujold on Star Trek: Voyager (1995), both she and Bujold have each co-starred opposite Richard Burton in a film.
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