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- Meet a child genius named Sheldon Cooper (already seen as an adult in The Big Bang Theory (2007)) and his family. Some unique challenges face Sheldon, who is socially impaired.
- A drama centered on the personal and professional lives of five surgical interns and their supervisors.
- A chemistry teacher diagnosed with inoperable lung cancer turns to manufacturing and selling methamphetamine with a former student in order to secure his family's future.
- A ranching family in Montana faces off against others encroaching on their land.
- Two brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons, and gods that roam the earth.
- On the run from a drug deal gone bad, brilliant college dropout Mike Ross finds himself working with Harvey Specter, one of New York City's best lawyers.
- New Jersey mob boss Tony Soprano deals with personal and professional issues in his home and business life that affect his mental state, leading him to seek professional psychiatric counseling.
- Anthology series in which police investigations unearth the personal and professional secrets of those involved, both within and outside the law.
- Shaun Murphy, a young surgeon with autism and Savant syndrome, is recruited into the surgical unit of a prestigious hospital.
- An anthology series centering on different characters and locations, showcasing different aspects of horror.
- A scrappy, feisty, fiercely loyal Chicago family makes no apologies.
- The series follows Adrian Monk, a brilliant former San Francisco detective, who now consults the police as a private consultant whilst battling with an obsessive-compulsive disorder.
- Claire Beauchamp Randall, a nurse in World War II, mysteriously goes back in time to Scotland in 1743. There, she meets a dashing Highland warrior and gets drawn into an epic rebellion.
- The trials and tribulations of criminal lawyer Jimmy McGill in the years leading up to his fateful run-in with Walter White and Jesse Pinkman.
- Follows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- Various chronicles of deception, intrigue, and murder in and around frozen Minnesota. All of these tales mysteriously lead back one way or another to Fargo, North Dakota.
- Three different, but related, families face trials and tribulations in their own uniquely comedic ways.
- F.B.I. Special Agent Seeley Booth teams up with the Jeffersonian's top anthropologist, Dr. Temperance Brennan, to investigate cases where all that's left of the victims are their bones.
- Comedy series following the exploits of Det. Jake Peralta and his diverse, lovable colleagues as they police the NYPD's 99th Precinct.
- Follows District 21 of the Chicago Police Department, made up of two different groups: the uniformed cops and the Intelligence Unit.
- Two F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
- A new FBI profiler, Elizabeth Keen, has her entire life uprooted when a mysterious criminal, Raymond Reddington, who has eluded capture for decades, turns himself in and insists on speaking only to her.
- In a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.
- A hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.
- Follows the misadventures of four irreverent grade-schoolers in the quiet, dysfunctional town of South Park, Colorado.
- Lucifer Morningstar has decided he's had enough of being the dutiful servant in Hell and decides to spend some time on Earth to better understand humanity. He settles in Los Angeles - the City of Angels.
- Three parapsychologists forced out of their university funding set up shop as a unique ghost removal service in New York City, attracting frightened yet skeptical customers.
- The doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- Set 97 years after a nuclear war destroyed civilization, when a spaceship housing humanity's lone survivors sends 100 juvenile delinquents back to Earth, hoping to repopulate the planet.
- When a psychopath commits murders based on novelist Castle's books, Detective Beckett seeks his help to solve the case. He decides to work with her and uses his experiences as research for his novels.
- A young Clark Kent struggles to find his place in the world as he learns to harness his alien powers for good and deals with the typical troubles of teenage life in Smallville, Kansas.
- When a single mom and her two kids arrive in a small town, they begin to discover their connection to the original Ghostbusters and the secret legacy their grandfather left behind.
- A young woman with a troubled past is drawn to a small town in Maine where fairy tales are to be believed.
- After being struck by lightning, Barry Allen wakes up from his coma to discover he's been given the power of super speed, becoming the Flash, and fighting crime in Central City.
- Based on the true story of Jordan Belfort, from his rise to a wealthy stock-broker living the high life to his fall involving crime, corruption and the federal government.
- A chronicle of the lives of a dysfunctional family who run an independent funeral home in Los Angeles.
- As Alfred the Great defends his kingdom from Norse invaders, Uhtred--born a Saxon but raised by Vikings--seeks to claim his ancestral birthright.
- When a beautiful stranger leads computer hacker Neo to a forbidding underworld, he discovers the shocking truth--the life he knows is the elaborate deception of an evil cyber-intelligence.
- Four friends band together against an anonymous foe who threatens to reveal their darkest secrets, while also investigating the disappearance of their best friend.
- In the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- In ancient China, a group of European mercenaries encounters a secret army that maintains and defends the Great Wall of China against a horde of monstrous creatures.
- A bipolar CIA operative becomes convinced a prisoner of war has been turned by al-Qaeda and is planning to carry out a terrorist attack on American soil.
- A blind lawyer by day, vigilante by night. Matt Murdock fights the crime of New York as Daredevil.
- Still reeling from the loss of Gamora, Peter Quill rallies his team to defend the universe and one of their own - a mission that could mean the end of the Guardians if not successful.
- Return to a world of two realities: one, everyday life; the other, what lies behind it. To find out if his reality is a construct, to truly know himself, Mr. Anderson will have to choose to follow the white rabbit once more.
- A fashion model celebrity couple join an eventful cruise for the super-rich.
- The misadventures of a talking sea sponge who works at a fast food restaurant, attends a boating school, and lives in an underwater pineapple.
- A police investigation, the saga of a grieving family, and a Seattle mayoral campaign all interlock after the body of 17-year-old Rosie Larsen is found in the trunk of a submerged car.
- In the ancient battle of Thermopylae, King Leonidas and 300 Spartans fight against Xerxes and his massive Persian army. They face insurmountable odds when they are betrayed by a Spartan reject.
- Four people and their otherworldly frienemy struggle in the afterlife to define what it means to be good.