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- Three friends, now partners in a medical practice, share their professional and personal lives.
- Picking up where the WE tv one-hour special OMG! Sextuplets! leaves off, in this one-hour continuing series, we find out how life with the Masche family entails all the craziness that any new parents face - times six!
- After a three-year struggle to conceive, Jenny and Bryan Masche find their wishes have multiplied when the news that they're expecting six babies rocks their world. Jenny's contractions come way too early, and she is admitted to the hospital where she remains under close observation. As the weeks turn into months, the confinement and medication takes its toll - Jenny is challenged mentally and physically. When the big day finally comes, the sextuplets hold their own after birth, but Jenny goes into heart failure and must be rushed to Intensive Care. She fights for her life. Five days later she's recovered enough to visit her six tiny babies in the NICU for the first time. Newspaper headlines about the birth of the sextuplets draw the attention of the DEAL OR NO DEAL casting team, and Jenny is selected to compete on the show. She and the entire family head to Hollywood, where the babies make their television debut. Jenny wins more than one hundred thousand dollars for the babies' college fund and she and Bryan head home to Arizona to continue their ever-changing adventure as a family of eight.
- In this update of the original special "Double Identical Twins," we follow the further adventures of the Morris family, who grew from three members to seven after the birth of an extremely rare set of quads: two identical boys and two identical girls. These days Kurt and Geana Morris have their hands full with big brother Sammy (now 6) and four busy 4 year-olds: Anna, Ella, James and Robbie. After re-capping the birth of the quads and the highlights of their first three years (including footage of the family from the update special" Babies, Babies, Everywhere"), we're off and running in the midst their hectic lives today. Since we saw the quads last, they've done a lot of growing, and the family has braved medical and life challenges including a serious accident that landed Sammy in the E.R. and a fire in the family home. While all the kids are adorable and engaging, Anna has been diagnosed with a mild form of Cerebral Palsy, Ella may have hearing problems, and the two boys continue in behavioral and motor skills therapy. Meanwhile, Kurt and Geana do their best to juggle family, their relationship and careers - braving it all with a sense of humor and a determination to live their best lives.
- In this one-hour special, cameras follow the cases of three babies with serious medical challenges and the dream team of specialists fighting to save their lives. After the babies' conditions are diagnosed in utero, delicate pre-birth procedures and their subsequent deliveries are documented at Hollywood Presbyterian Medical Center. Immediately after birth, the documentary team follows the urgent transports of two of the newborns to Children's Hospital Los Angeles and chronicles their stabilization and the life-and-death surgeries their survival requires.