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- Meet a child genius named Sheldon Cooper (already seen as an adult in The Big Bang Theory (2007)) and his family. Some unique challenges face Sheldon, who is socially impaired.
- A drama centered on the personal and professional lives of five surgical interns and their supervisors.
- He's smart. He's lovable. He's Dexter Morgan, America's favorite serial killer, who spends his days solving crimes and nights committing them.
- Follows the Major Case Response Team (MCRT) from the Naval Criminal Investigative Service (NCIS), as they get to the bottom of criminal cases connected to Navy and Marine Corps personnel.
- A chemistry teacher diagnosed with inoperable lung cancer turns to manufacturing and selling methamphetamine with a former student in order to secure his family's future.
- Explores the high-pressure experiences of the first responders who are thrust into the most frightening, shocking, and heart-stopping situations.
- Using a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- New Jersey mob boss Tony Soprano deals with personal and professional issues in his home and business life that affect his mental state, leading him to seek professional psychiatric counseling.
- Two brothers follow their father's footsteps as hunters, fighting evil supernatural beings of many kinds, including monsters, demons, and gods that roam the earth.
- The series follows Adrian Monk, a brilliant former San Francisco detective, who now consults the police as a private consultant whilst battling with an obsessive-compulsive disorder.
- A scrappy, feisty, fiercely loyal Chicago family makes no apologies.
- Shaun Murphy, a young surgeon with autism and Savant syndrome, is recruited into the surgical unit of a prestigious hospital.
- Claire Beauchamp Randall, a nurse in World War II, mysteriously goes back in time to Scotland in 1743. There, she meets a dashing Highland warrior and gets drawn into an epic rebellion.
- Various chronicles of deception, intrigue, and murder in and around frozen Minnesota. All of these tales mysteriously lead back one way or another to Fargo, North Dakota.
- Follows the personal and professional lives of six twenty to thirty year-old friends living in the Manhattan borough of New York City.
- Three different, but related, families face trials and tribulations in their own uniquely comedic ways.
- Comedy series following the exploits of Det. Jake Peralta and his diverse, lovable colleagues as they police the NYPD's 99th Precinct.
- The continuing misadventures of neurotic New York City stand-up comedian Jerry Seinfeld and his equally neurotic New York City friends.
- The quirky spin on Conan Doyle's iconic sleuth pitches him as a "high-functioning sociopath" in modern-day London. Assisting him in his investigations: Afghanistan War vet John Watson, who's introduced to Holmes by a mutual acquaintance.
- Two F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
- A new FBI profiler, Elizabeth Keen, has her entire life uprooted when a mysterious criminal, Raymond Reddington, who has eluded capture for decades, turns himself in and insists on speaking only to her.
- A hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.
- This spinoff of the critically acclaimed show Grey's Anatomy follows the lives of the men and women of firehouse station 19 in Seattle, Washington.
- Privileged teens living on the Upper East Side of New York can hide no secret from the ruthless blogger who is always watching.
- Set almost 100 years after Captain Kirk's 5-year mission, a new generation of Starfleet officers sets off in the U.S.S. Enterprise-D on its own mission to go where no one has gone before.
- Professional writer and amateur sleuth Jessica Fletcher uses her intellect, charm, and persistence to get to the bottom of every crime she encounters.
- When the menace known as the Joker wreaks havoc and chaos on the people of Gotham, Batman must accept one of the greatest psychological and physical tests of his ability to fight injustice.
- The doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- Three parapsychologists forced out of their university funding set up shop as a unique ghost removal service in New York City, attracting frightened yet skeptical customers.
- In Las Vegas, a squad of forensic investigators are trained to solve crimes by meticulously examining the evidence. They employ advanced technology and their rationality to detect the perpetrators.
- A young Clark Kent struggles to find his place in the world as he learns to harness his alien powers for good and deals with the typical troubles of teenage life in Smallville, Kansas.
- When a beautiful stranger leads computer hacker Neo to a forbidding underworld, he discovers the shocking truth--the life he knows is the elaborate deception of an evil cyber-intelligence.
- Based on the true story of Jordan Belfort, from his rise to a wealthy stock-broker living the high life to his fall involving crime, corruption and the federal government.
- Goaded by his buddies, a nerdy guy who's never "done the deed" only finds the pressure mounting when he meets a single mother.
- A chronicle of the lives of a dysfunctional family who run an independent funeral home in Los Angeles.
- Los Angeles homicide detective Lieutenant Columbo uses his humble ways and ingenuous demeanor to winkle out even the most well-concealed of crimes.
- Two detectives, a rookie and a veteran, hunt a serial killer who uses the seven deadly sins as his motives.
- In the unreal world of Sacred Heart Hospital, intern John "J.D." Dorian learns the ways of medicine, friendship and life.
- A promising young drummer enrolls at a cut-throat music conservatory where his dreams of greatness are mentored by an instructor who will stop at nothing to realize a student's potential.
- A gifted young teen tries to survive life with his dimwitted, dysfunctional family.
- An ex-hitman comes out of retirement to track down the gangsters who killed his dog and stole his car.
- After a tragic accident, two stage magicians in 1890s London engage in a battle to create the ultimate illusion while sacrificing everything they have to outwit each other.
- When Guy, a bank teller, learns that he is a non-player character in a bloodthirsty, open-world video game, he goes on to become the hero of the story and takes the responsibility of saving the world.
- The misadventures of a talking sea sponge who works at a fast food restaurant, attends a boating school, and lives in an underwater pineapple.
- Three Halliwell sisters discover that they are descendants of a line of good female witches and are destined to fight against the forces of evil, using their combined power of witchcraft known as the "Power of Three".
- A linguist works with the military to communicate with alien lifeforms after twelve mysterious spacecraft appear around the world.
- In the ancient battle of Thermopylae, King Leonidas and 300 Spartans fight against Xerxes and his massive Persian army. They face insurmountable odds when they are betrayed by a Spartan reject.
- After being bitten by a genetically-modified spider, a shy teenager gains spider-like abilities that he uses to fight injustice as a masked superhero and face a vengeful enemy.
- Epic series reveals the scandalous life of a young king whose affairs and obsession with producing a male heir changed marriage, the church, and the world.
- NCIS's covert operations team go undercover to investigate cases involving terrorism and National Security.