Title refers to Judy Collins' song, "Both Sides Now".
This episode takes place October 29, 2016. The Date is shown on the tablet Amelia looks at after speaking with April.
Lina Green and Erica Jaye Green, who play sisters in this episode, are identical twin sisters in real life.
When Warren and Hunt are discussing what to do about the crying baby, Warren refers to Harriet as "him"
When Amelia enters the ER she is holding a large purse, presumably to cover her baby bump. Caterina Scorsone gave birth to her second child in November 2016.