- Dr. Meredith Grey: [opening voiceover] Defeat isn't an option. Not for surgeons. We don't back away from the table till the last breaths long gone. Terminal's a challenge. Life threatening's what gets us out of bed in the morning. We're not easily intimidated. We don't flinch, we don't back down, and we certainly don't surrender. Not at work anyway.
- Dr. Meredith Grey: [closing voiceover] To do our jobs, we have to believe defeat is not an option. That no matter how sick our patients get, there's hope for them. But even when our hopes give way to reality and we finally have to surrender to the truth, it just means we've lost today's battle, not tomorrow's war. Here's the thing about surrender: once you do it, actually give in, you forget why you were even fighting in the first place.
- Dr. Derek Shepherd: [to Meredith] I didn't think you wanted to wear a wedding dress.
- Dr. Meredith Grey: I don't! How does he even know we're engaged?
- Dr. Derek Shepherd: Richard's my friend. He's not the one that ordered the dress. If you don't wanna wear a wedding dress, talk to Izzie.
- Dr. Meredith Grey: Oh, yeah! As the chemo drips into her cancer-y arm, and she looks at me with those cancer-y eyes, those cancer-y wedding loving eyes...
- Dr. Derek Shepherd: Be strong.
- Dr. Meredith Grey: We will have bridesmaids in pink taffeta! And you will be wearing a top hat and a morning coat! And somebody will be singing wind beneath my fricking wings!
- Dr. Callie Torres: My dad is taking me home. He's talking to the Chief and he's making me quit my job, and quit my relationship which he has yet to acknowledge even exists.
- Dr. Mark Sloan: What are you, twelve? Tell him he's crazy.
- Dr. Callie Torres: You don't understand. There isn't anything he hasn't done for me. Okay. Nothing. He's paid for my college, he's paid for med school, I have a huge trust fund because he doesn't want me to worry about anything but being a great doctor. I mean, the man has done nothing but support me his whole life.
- Dr. Mark Sloan: Supporting someone and respecting someone aren't the same thing. You need to tell him that.
- Dr. Derek Shepherd: [after Derek chooses Webber to be his best man in the wedding] When are you gonna let go of the grudge you have against the Chief?
- Dr. Meredith Grey: Derek, the man had an affair with my mother, broke up my parents' marriage and basically destroyed my childhood. Meanwhile, you've been best friends with Mark for 20 years and you're willing to throw all that away over nothing. So, don't talk to me about holding grudges. I'll get over mine when you get over yours.
- Dr. Richard Webber: [to Mr. Torres] I'm... I'm sorry, y... you wanna take Dr. Torres home?
- Carlos Torres: Now, I reconize that my daughter's a senior resident and you've invested in her education. I'm happy to write out a check in whatever amount, as a donation to your hospital. In exchange, I would ask you to transfer her to St. Mary's in Miami.
- Dr. Richard Webber: I appreciate the offer, sir, but with all due respect, your daughter is a grown woman. Does she know you're here?
- Carlos Torres: You don't have children, do you?
- Dr. Richard Webber: No, no, no, I don't.
- Carlos Torres: No, you don't, because if you did... your daughter's a grown woman. I mean, that... that means nothing. She's my child. It's like blood running through your veins, you don't outgrow it... it never goes away, the love. The need to protect them, from everything... from everything, even from themselves. They grow up, they move out, they change, become people you don't even reconize, make decisions... I mean, and they think you don't love them, because you don't understand, but it's the opposite. See, it's the opposite. You fight for them, always. You never surrender. When your child is on the line, you never surrender.
- Dr. Izzie Stevens: All I wanted to do today was flip through magazines, and call caterers, and make Mer try on dresses I knew she'd hate. I thought it would be fun, or funny. I thought I could be the same person I was when I woke up this morning, but I'm not. I'm just another patient trapped inside a sick, dying, cancer-ridden body.