Chloe tries to bring light to the rising threat from the animals. Jackson is taken to a hospital and while they are there Mitch works to create a cure. However, there are many obstacles they must overcome.
Chloe is taken hostage by someone she knows. Jackson and the others are arrive at Zambia to find the leopard to test Mitch's theory of the animal mutation.
Following the dramatic shift in violent animal behavior, the team attempts to rescue Jamie and the leopard whose DNA may hold the key to curing the animal crisis.
The team travels to Portugal where they square off against a dangerous venom dealer in order to get one step closer to the cure. Also, Jackson's increasingly erratic behavior jeopardizes the entire team.
Jackson faces the most difficult decision of his life. Also, Mitch reluctantly enlists help from his father, Max Morgan (Robin Thomas), to investigate the origin of the final set of triple helix animal bones.