In the beginning, when Priya Mehra drops Krishna and Rohit at their offices, in one scene Rohit is not in the front seat of car and in the next scene he is.
During Krishna's birthday party, his shirt changes between shots from half to full then half again.
The airplane rescued by Krrish is an Airbus A380; these were banned in India until December 2013.
Initially in the movie Kaal says that he can't stand because of defective bone marrow, but at the end Kaal takes out the bone marrow of Rohit; despite of this operation Rohit stands without any support to heal Krrish.
In one scene at Kaal's lab, Namibia is shown on a map of South America.