- Was at the scene of the accident of actor Paul Walker. Paul was killed on impact when a car that he was riding in crashed and burst into flames. Shane was one of the first people to be interviewed by the press about the accident.
- At the age of fourteen Shane was jumped by seven kids at school and beaten so severely that he was left with permanent damage to his eyes and jaw. Two months later he was in a snow-boarding accident and suffered a concussion and temporary amnesia. Over the course of the following year he experienced memory lapses (at one point not knowing what the alphabet was), occasional fainting and other concerning affects. However, various MRI testing was done and nothing turned up in the reports.
- Son of editor Bret Hampton. Grandson and great nephew of former Disney animators and acclaimed western artists, Roy Hampton and Bill Hampton. Step-second-cousin of actress Wendi McLendon-Covey.
- Some of his Top 100 favorite films include Rocky (1976), Taxi Driver (1976), Swingers (1996), True Romance (1993), Lilya 4-Ever (2002), Hustle & Flow (2005), The Conversation (1974), Zodiac (2007), A Woman Under the Influence (1974), Michael Clayton (2007), Dead Presidents (1995), Pump Up the Volume (1990), Out of Sight (1998), Play Misty for Me (1971), Training Day (2001), Marathon Man (1976), Sideways (2004), 8 Mile (2002), Weekend at Bernie's (1989), Blow Out (1981), Mikey and Nicky (1976), Absence of Malice (1981), Collateral (2004), Out for Justice (1991), Changeling (2008), The Kid (1921), American Graffiti (1973), Man on Fire (2004), Wendy and Lucy (2008), The Thin Blue Line (1988), Badlands (1973), American Psycho (2000), U Turn (1997), The Limey (1999), In the Bedroom (2001), Jackie Brown (1997), Chinatown (1974), Heaven Knows What (2014), The French Connection (1971), Heat (1995) and Bloodsport (1988).
- Lives a "straight-edge lifestyle".
- Has vitiligo.
- He shared his first acting kiss with Christina, the girl next door to him whom he grew up with. Christina was killed by a drunk driver at the age of 20. They only worked on the one film together. Shane later made a short film in her memory as an anti drunk driving PSA.
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