- Best remembered for her portrayal of Donna, the blonde Anglo girlfriend of Lou Diamond Phillips in La Bamba (1987), the biopic of ill-fated pop singer Ritchie Valens.
- Her husband James Fearnley is the accordion player for the Irish rock group The Pogues.
- Has a production company with Mia Sara.
- The movie God's Lonely Man (1996) was a family affair. Danielle was a producer; father Frank von Zerneck served as executive producer; brother Francis von Zerneck took on directing/writing chores; actress/mom Julie Mannix had a bit role; and musician/husband James Fearnley provided the original music.
- Studied drama at NYU and at the Playwright's Horizon.
- One of her first professional jobs was, at age 16, on General Hospital (1983), wherein she played "Lou Swenson".
- Daughter of Frank von Zerneck and Julie Mannix.
- Grandaughter of Peter von Zerneck and Daniel P. Mannix.
- Older sister of Francis von Zerneck and Kathy Hatfield.
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