- Graduate of Columbia University and Harvard Law School.
- Despite his multiple appearances on the Comedy Central Roasts, being a series regular on Lewis Black's Root of All Evil (2008), and even having his own show on the network, he had only one stand-up special on Comedy Central, which was the 2009 "Greg Giraldo: Midlife Vices" (2009) (TV)_ show.
- Rushed to a New Jersey hospital on September 25, 2010, after an accidental drug overdose.
- Was a lawyer for less than a year before he changed his profession to comedy.
- On March 18, 2011, Comedy Central aired a tribute to Greg titled Give It Up for Greg Giraldo (2011). Fellow comedians Sarah Silverman, 'Nick Swardson'', Lewis Black, Conan O'Brien, Denis Leary, Dave Attell, and Jeffrey Ross (to name a few) gave very emotional heartfelt condolences to Greg.
- Was of Colombian and Spanish descent.
- Performed his last stand-up show on September 24, 2010, in New Jersey.
- Had his own show on Comedy Central for a brief period of time, titled "Stand-Up Nation with Greg Giraldo" (2005)_.
- Worked for the New York City law firm Skadden, Arps, Slate, Meagher & Flom.
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