- Her parents gave her the nickname Busy, because as an infant she was always moving, the name stuck, and it even appears on her credit cards.
- At 17, she worked the toy fair circuit as a real-life Barbie before making her show-business debut.
- Filmed a pilot for a 2004 TV series for NBC called "Foster Home" with Macaulay Culkin, but the show was never picked up.
- Longtime best friends with Dawson's Creek (1998) co-star Michelle Williams.
- One of Busy's hobbies is designing, creating, and baking very intricate, theme based, custom designed cakes, such as a multiple level cake based on the movie Tangled (2010) (based on the fairy tale "Rapunzel"), which she made for her 3 1/2 year old daughter, Birdie. Busy brought pictures of the "Tangled cake" for her March 14, 2012 appearance on Jimmy Kimmel Live! (2003).
- Has two children: Birdie Leigh Silverstein (b. August 13, 2008) and daughter Cricket Pearl Silverstiein (b July 2, 2013) with her husband Marc Silverstein,.
- She attended Loyola Marymount University at the same time as Colin Hanks, Linda Cardellini and Sarah Vato.
- Has a "story by" credit in Blades of Glory (2007).
- Auditioned for the role of Lindsay Weir on Freaks and Geeks (1999) before being cast as Kim Kelly.
- (September 9, 2017) Landed in Mass General Hospital after hitting the town in Boston in honor of BFF Michelle Williams's birthday. The inseparable duo was spotted strolling in the Seaport neighborhood wearing a birthday gift from Philipps: matching "Best Friends" leather jackets. But later, the night took a turn when Philipps landed in the hospital with terrible pains in her left side, which she said was determined to be caused by ovarian torsion.
- Raised in Scottsdale, Arizona.
- Was born on the same day (four years apart) as close friend and Freaks and Geeks (1999) co-star Linda Cardellini.
- Friend of James Franco, since meeting on Freaks and Geeks (1999).
- Her favorite movie is Noah Baumbach's Kicking and Screaming (1995).
- She attended Chaparral High School in Scottsdale, where she was taught by high-school theatre teacher Deborah Carrick.
- Auditioned for the television show Roswell (1999).
- In July 2017, Busy and actor/director/writer Steve Agee began a podcast called "We're No Doctors". The podcast's description says 'Meet Steve and Busy, two neurotic, hypochondriac actors who've decided to host a podcast about health and medicine. Join them on a weekly journey to unload their health issues, obsessions and opinions.'.
- Had an abortion at age 15.
- Loves Mexican food.
- Attended Chaparral High School in Scottsdale, AZ.
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